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Publication : A mouse model to study tau pathology related with tau phosphorylation and assembly.

First Author  Engel T Year  2007
Journal  J Neurol Sci Volume  257
Issue  1-2 Pages  250-4
PubMed ID  17362999 Mgi Jnum  J:126826
Mgi Id  MGI:3762074 Doi  10.1016/j.jns.2007.01.047
Citation  Engel T, et al. (2007) A mouse model to study tau pathology related with tau phosphorylation and assembly. J Neurol Sci 257(1-2):250-4
abstractText  The role of tau phosphorylation and tau aggregation in the pathology of a transgenic mouse model that overexpresses GSK-3beta and FTDP-17 tau has been analyzed. In that model we have suggested a possible role for tau phosphorylation, but not for tau aggregation, in the cognitive impairment found in the transgenic mouse.
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