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Allele : Tg(Igh3H9)41Mwg transgene insertion 41, Martin Weigert

Primary Identifier  MGI:3776392 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Igh3H9)41Mwg
Strain of Origin  (C57BL/6 x SJL)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  The rearranged heavy chain VDJ gene segments and the IgM constant domain were isolated from the murine B cell clone 3H9. Transgenic mice were generated and expression of the transgene confirmed by primer extension analysis of spleen RNA. The heavy chain expressed by this transgene is able to heterodimerize with endogenous Ig light chains to produce IgM antibodies that have a high affinity for DNA similar to the antibody produced by the 3H9 clone.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(Igh-6*3H9)41Tnm,
  • VH3H9,
  • Tg(Igh-6*3H9)41Tnm,
  • VH3H9
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

13 Publication categories

Trail: Allele