|  Help  |  About  |  Contact Us

Allele : Pth2r<tm1.1Tbu> parathyroid hormone 2 receptor; targeted mutation 1.1, Ted B Usdin

Primary Identifier  MGI:6330764 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pth2r
Transmission  Germline Strain of Origin  (129 x C57BL/6)F1
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site was inserted into intron 4 and a neomycin resistance gene cassette and a second loxP site into intron 5. The floxed exon 5 and the neo cassette were deleted through subsequent cre-mediated recombination. Exon 5 contains a transmembrane domain and its deletion causes a frameshift, creating a null allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele