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Publication : Egg production of Clonorchis sinensis in different strains of inbred mice.

First Author  Kim JI Year  1992
Journal  Kisaengchunghak Chapchi Volume  30
Issue  3 Pages  169-75
PubMed ID  1420029 Mgi Jnum  J:27891
Mgi Id  MGI:75526 Doi  10.3347/kjp.1992.30.3.169
Citation  Kim JI, et al. (1992) Egg production of Clonorchis sinensis in different strains of inbred mice. Kisaengchunghak Chapchi 30(3):169-75
abstractText  In order to compare the intraspecific variation in host-parasite relationship of Clonorchis sinensis, six strains of inbred mice, ICR, DDY, GPC, BALB/c, nude and DS, were infected orally with 20 metacercariae of C. sinensis. The biologic incubation period of C. sinensis was the shortest in DDY mice, 21.2 days in average, followed by GPC 21.4, BALB/c and DS 23.2, ICR and nude 23.4 days, respectively. The fertile period of the fluke was also the longest in the DDY strain, 164 days on average, followed by GPC 132, BALB/c 97, nude 37, DS 32 and ICR 28 days. The egg-laying capacity of the fluke in DDY and GPC was relatively high and stable compared with the other four strains of mice. It was found that there are intraspecific variations in biologic incubation period, fertile period, and fecundity of C. sinensis. The DDY mouse is likely to be the most suitable experimental animal among the six strains of the mice tested.
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