| Primary Identifier | MGI:1913096 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 57748 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables transcription coactivator activity. Involved in actin nucleation; actin polymerization-dependent cell motility; and positive regulation of apoptotic process. Acts upstream of or within intrinsic apoptotic signaling pathway by p53 class mediator and regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in skeletal muscle. Orthologous to human JMY (junction mediating and regulatory protein, p53 cofactor). PHENOTYPE: Mice homozygous for a conditional allele activated in Sertoli cells exhibit reduced male fertility, oligozoospermia, asthenozoospermia, enlarged sperm head, and impaired Sertoli cell function. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
