| Primary Identifier | MGI:1917711 | Organism | mouse, laboratory |
| Chromosome | 7 | NCBI Gene Number | 70461 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable cAMP response element binding protein binding activity. Acts upstream of or within several processes, including energy homeostasis; negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway; and positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Orthologous to human CRTC3 (CREB regulated transcription coactivator 3). PHENOTYPE: Mice homozygous for a null mutation display resistance to diet-induced obesity, increased energy expenditure, decreased white adipose tissue mass, increased brown adipose cell numbers, and increased core temperature. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
