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Protein Coding Gene : Tecpr1 tectonin beta-propeller repeat containing 1

Primary Identifier  MGI:1917631 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  70381
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in autophagosome maturation and regulation of autophagosome maturation. Predicted to be located in nucleoplasm. Predicted to be active in autophagosome membrane and lysosomal membrane. Is expressed in several structures, including alimentary system; brain; cochlea; ganglia; and vibrissa follicle. Orthologous to human TECPR1 (tectonin beta-propeller repeat containing 1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired selective autophagy and abnormal response to bacterial infection in MEFs. [provided by MGI curators]
  • synonyms:
  • Tecpr1,
  • tectonin beta-propeller repeat containing 1,
  • mKIAA1358,
  • 2210010N04Rik,
  • RIKEN cDNA 2210010N04 gene

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