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Protein Coding Gene : Mep1b meprin 1 beta

Primary Identifier  MGI:96964 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  17288
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable identical protein binding activity and metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to act upstream of or within inflammatory response. Located in membrane. Is expressed in cortical early distal tubule; cortical early proximal tubule; intestine; intestine epithelium; and metanephros. Orthologous to human MEP1B (meprin A subunit beta).
PHENOTYPE: Homozygotes for a targeted null mutation exhibit 50% prenatal lethality; survivors have reduced birth weight and show altered renal gene expression, but otherwise are apparently normal. [provided by MGI curators]
  • synonyms:
  • Mep1b,
  • MGD-MRK-12195,
  • MGD-MRK-12198,
  • Mep-1b,
  • meprin 1 beta,
  • meprin beta

Features --> Cross References

Genome

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0 CDSs

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0 Involved In Mutations

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0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For