First Author | Heidmann O | Year | 1986 |
Journal | Science | Volume | 234 |
Issue | 4778 | Pages | 866-8 |
PubMed ID | 3022377 | Mgi Jnum | J:8468 |
Mgi Id | MGI:56934 | Doi | 10.1126/science.3022377 |
Citation | Heidmann O, et al. (1986) Chromosomal localization of muscle nicotinic acetylcholine receptor genes in the mouse. Science 234(4778):866-8 |
abstractText | The chromosomal localization of the genes encoding the four subunits of muscle nicotinic receptor was determined by analyzing restriction fragment length polymorphisms between two mouse species Mus musculus domesticus (DBA/2) and Mus spretus (SPE). Analysis of the progeny of the interspecies mouse backcross (DBA/2 X SPE) X DBA/2 showed that the alpha-subunit gene cosegregates with the alpha-cardiac actin gene on chromosome 17, that the beta-subunit gene is located on chromosome 11, and that the gamma- and delta-subunit genes cosegregate and are located on chromosome 1. |