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Publication : Chromosomal localization of muscle nicotinic acetylcholine receptor genes in the mouse.

First Author  Heidmann O Year  1986
Journal  Science Volume  234
Issue  4778 Pages  866-8
PubMed ID  3022377 Mgi Jnum  J:8468
Mgi Id  MGI:56934 Doi  10.1126/science.3022377
Citation  Heidmann O, et al. (1986) Chromosomal localization of muscle nicotinic acetylcholine receptor genes in the mouse. Science 234(4778):866-8
abstractText  The chromosomal localization of the genes encoding the four subunits of muscle nicotinic receptor was determined by analyzing restriction fragment length polymorphisms between two mouse species Mus musculus domesticus (DBA/2) and Mus spretus (SPE). Analysis of the progeny of the interspecies mouse backcross (DBA/2 X SPE) X DBA/2 showed that the alpha-subunit gene cosegregates with the alpha-cardiac actin gene on chromosome 17, that the beta-subunit gene is located on chromosome 11, and that the gamma- and delta-subunit genes cosegregate and are located on chromosome 1.
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