Primary Identifier | MGI:1914192 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 66942 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable several functions, including ATP binding activity; RNA binding activity; and RNA helicase activity. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in chromosome. Predicted to be active in nucleolus. Orthologous to human DDX18 (DEAD-box helicase 18). PHENOTYPE: Mice homozygous for a null allele display peri-implantation lethality with loss of pluripotency in early development. [provided by MGI curators] |