| Primary Identifier | MGI:1201608 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 12123 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to be involved in cellular response to potassium ion starvation; positive regulation of cellular component organization; and positive regulation of neuron apoptotic process. Predicted to act upstream of or within apoptotic process. Predicted to be located in membrane. Predicted to be active in mitochondrion. Is expressed in central nervous system; epidermis; olfactory epithelium; and peripheral nervous system ganglion. Orthologous to human HRK (harakiri, BCL2 interacting protein). PHENOTYPE: Homozygous mutants exhibit motoneurons that are protected from cell death induced by resection of the hypoglossal nerve and delayed cell death of superior cervical ganglia neurons triggered by nerve growth factor withdrawal. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
