| Primary Identifier | MGI:103159 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 12700 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity. Acts upstream of or within protein kinase C-activating G protein-coupled receptor signaling pathway. Located in plasma membrane. Is expressed in liver; retina; and thymus primordium. Human ortholog(s) of this gene implicated in malaria and tuberculosis. Orthologous to human CISH (cytokine inducible SH2 containing protein). PHENOTYPE: Mice homozygous for a knock-out allele exhibit enhanced Th2 and Th9 differentiation and allergic airway inflammation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
