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Protein Coding Gene : Sytl2 synaptotagmin-like 2
Primary Identifier  MGI:1933366 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  83671
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables neurexin family protein binding activity. Involved in exocytosis and positive regulation of mucus secretion. Acts upstream of or within protein localization to plasma membrane. Located in melanosome and plasma membrane. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human SYTL2 (synaptotagmin like 2).
PHENOTYPE: Mice homozygous for a null allele display abnormal gastric surface mucus cell morphology and reduced basal mucin secretion from gastric cells [provided by MGI curators]
  • synonyms:
  • Slp2-b,
  • Sytl2,
  • AI266830,
  • MGI:2141893,
  • Slp2-c,
  • synaptotagmin-like 2,
  • expressed sequence AI266830,
  • Slp2-d,
  • Slp2,
  • Slp2-a
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Features --> Cross References

Genome

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4 Involved In Mutations

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

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Disease

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