|  Help  |  About  |  Contact Us

Allele : Chrna7<tm3.1Swr> cholinergic receptor, nicotinic, alpha polypeptide 7; targeted mutation 3.1, Scott W Rogers

Primary Identifier  MGI:5763561 Allele Type  Targeted
Attribute String  Reporter Gene  Chrna7
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  Exon 7 was modified to contain two nucleotide changes (CT to GG) that result in the amino acid substitution of alanine for glutamic acid at position 260 (E260A). A C-terminal hemagglutinin (HA) epitope tag (YPYDVPDY) was inserted. The IRES, MAPT (tau) and GFP reporter fusion was inserted into the 3' UTR. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted downstream of the reporter fusion.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • alpha7<E260A>,
  • E260A Chrna7-IRES-tauGFP mice,
  • alpha7<E260A>,
  • E260A Chrna7-IRES-tauGFP mice
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories

Trail: Allele