| Primary Identifier | MGI:1349392 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 26914 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables ADP-D-ribose binding activity; ADP-D-ribose modification-dependent protein binding activity; and chromatin binding activity. Involved in regulation of nucleobase-containing compound metabolic process; regulation of oxidative phosphorylation; and regulation of response to oxidative stress. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in condensed chromosome. Is active in nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study myelodysplastic syndrome. Orthologous to human MACROH2A1 (macroH2A.1 histone). PHENOTYPE: Mice homozygous for one knock-out allele are viable and fertile and display no gross phenotypic abnormalities. Mice homozygous for a different knock-out allele exhibit female-specific hepatic steatosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
