| First Author | Hsieh CL | Year | 1991 |
| Journal | Cytogenet Cell Genet | Volume | 56 |
| Issue | 3-4 | Pages | 160-3 |
| PubMed ID | 1711435 | Mgi Jnum | J:11269 |
| Mgi Id | MGI:59708 | Doi | 10.1159/000133076 |
| Citation | Hsieh CL, et al. (1991) Chromosomal localization of the gene for AA-type platelet-derived growth factor receptor (PDGFRA) in humans and mice. Cytogenet Cell Genet 56(3-4):160-3 |
| abstractText | The full-length cDNA of the receptor for human AA-type platelet-derived growth factor (PDGF) was used to assign the PDGFRA gene to region q11----q21 of human chromosome 4 and to mouse Chromosome 5 by somatic cell hybrid analysis. Since the same region also contains the c-kit oncogene homolog KIT, we carried out pulsed-field gel electrophoresis to determine the physical distance between the two genes in human DNA. The two probes, when successively applied to the same filters, hybridized to a 450-kb EagI-fragment but not to other common restriction fragments. The genes are separated by at least one NotI, one XhoI, and one SalI site. |
