| Primary Identifier | MGI:7627370 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Ighg2c |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 technology generated a GGG to AGG change resulting in a glycine to arginine substitution at position 400 (p.G400R). The mouse G400R mutation corresponds to the human G396R protective Asia-specific variant for progression and survival of colorectal cancer patients. |
