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Allele : Relb<tm1.1Alex> avian reticuloendotheliosis viral (v-rel) oncogene related B; targeted mutation 1.1, Alexander Hoffmann
Primary Identifier  MGI:7561998 Allele Type  Targeted
Gene  Relb Transmission  Germline
Strain of Origin  C57BL/6NTac Is Recombinase  false
Is Wild Type  false
molecularNote  The targeting vector is designed to insert three point mutations (R117A / Y120A / E123A) in the 5' region of the gene. The mutations result in loss of κB-site specific DNA binding. The targeting construct also included an FRT-flanked neomycin (neo) cassette Flp-mediated recombination removed the neo cassette.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Relb<Db>,
  • Relb<Db>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

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Trail: Allele




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