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Protein Coding Gene : Rps6ka2 ribosomal protein S6 kinase, polypeptide 2

Primary Identifier  MGI:1342290 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  20112
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0)

Enables ribosomal protein S6 kinase activity. Acts upstream of or within several processes, including cardiac muscle cell apoptotic process; oocyte maturation; and regulation of gene expression. Located in cytoplasm and meiotic spindle. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; nervous system; and sensory organ. Orthologous to human RPS6KA2 (ribosomal protein S6 kinase A2).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased response of heart to stress following transverse aortic constriction. [provided by MGI curators]
  • synonyms:
  • 90kDa,
  • D17Wsu134e,
  • ribosomal protein S6 kinase, polypeptide 2,
  • MGI:1098261,
  • MGD-MRK-35693,
  • Rps6ka2,
  • ribosomal protein S6 kinase, related sequence 1,
  • pp90rsk,
  • p90rsk,
  • DNA segment, Chr 17, Wayne State University 134, expressed,
  • Rsk3,
  • MGI:107228,
  • Rps6ka-rs1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

45 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For