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Protein Coding Gene : Pcbp2 poly(rC) binding protein 2

Primary Identifier  MGI:108202 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  18521
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables C-rich single-stranded DNA binding activity. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in central nervous system and sensory organ. Orthologous to human PCBP2 (poly(rC) binding protein 2).
PHENOTYPE: Mice heterozygous for a knock-out allele exhibit decreased body weight, impaired erythroblast maturation and lowered mean platelet counts. Mice homozygous for this allele die between E12.5 and E15.5 with hemorrhage and edema. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-37241,
  • MGI:2146212,
  • MGD-MRK-10809,
  • poly(rC) binding protein 2,
  • Pcbp2,
  • AW412548,
  • heterogeneous nuclear ribonucleoprotein X,
  • MGI:96165,
  • Hnrpx,
  • expressed sequence AW412548,
  • alphaCP-2

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For