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Allele : Gria2<tm1Phs> glutamate receptor, ionotropic, AMPA2 (alpha 2); targeted mutation 1, Peter H Seeburg

Primary Identifier  MGI:2178124 Allele Type  Targeted
Gene  Gria2 Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  Point mutations were introduced that altered the Q/R edited codon from one encoding glutamate to one encoding arginine (R). A loxP flanked neomycin resistance cassette was inserted into intron 11, 5' to the ECS site. Gria2 (GluR-B) gene expression is reduced by 30% compared to wild-type.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • GluR-B<Rneo>,
  • GluR-B<Rneo>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele