| First Author | Ball WD | Year | 1993 |
| Journal | Crit Rev Oral Biol Med | Volume | 4 |
| Issue | 3-4 | Pages | 517-24 |
| PubMed ID | 8374005 | Mgi Jnum | J:33004 |
| Mgi Id | MGI:80492 | Doi | 10.1177/10454411930040033701 |
| Citation | Ball WD, et al. (1993) The B1-immunoreactive proteins of the perinatal submandibular gland: similarity to the major parotid gland protein, RPSP. Crit Rev Oral Biol Med 4(3-4):517-24 |
| abstractText | The B1-immunoreactive proteins of type III cells of the perinatal rat submandibular gland are immunologically cross-reactive with proteins of both the sublingual and parotid glands; in particular, protein SMG-A appears similar to a major parotid protein. We isolated SMG-A and the parotid protein (known as M1 or leucine-rich protein), prepared polyclonal antibodies to them, and compared their biochemical properties and immunological reactivities. They were identical in their molecular weight on SDS-PAGE (23.5 kDa), tenacious binding to Affi-gel Blue, isoelectric point (pH 4.53), and proteolysis to a 14 kDa peptide: Antibodies to SMG-A showed reactivity with protein SMG-C, a product of the neonatal type I cells, as well as with proteins SMG-B1 and SMG-B2, contrasted with the absence of reactivity of anti-M1 IgG with these proteins. Anti-M1 reacted with the parotid secretory protein (PSP) of the mouse, and M1 appears to be the homologue, in the rat, of mouse PSP. |
