|  Help  |  About  |  Contact Us

Protein Coding Gene : Ifitm2 interferon induced transmembrane protein 2

Primary Identifier  MGI:1933382 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  80876
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Involved in negative regulation of viral entry into host cell and response to virus. Acts upstream of or within defense response to virus. Predicted to be located in early endosome membrane; late endosome membrane; and lysosomal membrane. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Is expressed in several structures, including 4-cell stage embryo; brain; genitourinary system; heart; and hemolymphoid system. Human ortholog(s) of this gene implicated in COVID-19. Orthologous to human IFITM2 (interferon induced transmembrane protein 2) and IFITM3 (interferon induced transmembrane protein 3).
  • synonyms:
  • Ifitm2,
  • Ifitm3l,
  • mil-3,
  • interferon induced transmembrane protein 2,
  • fragilis3,
  • interferon induced transmembrane protein 3-like

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For