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Protein Coding Gene : Gfra3 glial cell line derived neurotrophic factor family receptor alpha 3

Primary Identifier  MGI:1201403 Organism  mouse, laboratory
Chromosome  18 NCBI Gene Number  14587
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables axon guidance receptor activity. Acts upstream of or within axon guidance; neuron migration; and sympathetic nervous system development. Located in external side of plasma membrane. Is expressed in several structures, including adrenal medulla; alimentary system; cranial nerve; ganglia; and genitourinary system. Orthologous to human GFRA3 (GDNF family receptor alpha 3).
PHENOTYPE: Mice homozygous for disruption of this gene display ptosis and poor development of the sympathetic chain ganglia and associated nerves. [provided by MGI curators]
  • synonyms:
  • Gfra3,
  • Y15110,
  • expressed sequence Y15110,
  • GFR alpha-3,
  • glial cell line derived neurotrophic factor family receptor alpha 3,
  • MGI:2147424,
  • GFRalpha3

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For