|  Help  |  About  |  Contact Us

Protein Coding Gene : Xcr1 chemokine (C motif) receptor 1

Primary Identifier  MGI:1346338 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  23832
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable C-C chemokine binding activity and C-C chemokine receptor activity. Acts upstream of or within chemotaxis; release of sequestered calcium ion into cytosol; and response to cytokine. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including adrenal gland; central nervous system; immune system; intestine; and reproductive system. Orthologous to human XCR1 (X-C motif chemokine receptor 1).
PHENOTYPE: Mice homozygous for a targeted null mutation exhibit reduced CD8+ dendritic cell migration in response to XCL1. [provided by MGI curators]
  • synonyms:
  • GPR5,
  • chemokine (C motif) XC receptor 1,
  • Ccxcr1,
  • XCR1,
  • chemokine (C motif) receptor 1,
  • Xcr1,
  • C motif-1/lymphotactin receptor

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

5 Driver For