Primary Identifier | MGI:6121395 | Allele Type | Targeted |
Attribute String | Not Specified | Gene | Kdm2b |
Transmission | Germline | Strain of Origin | (C57BL/6 x 129S4/SvJae)F1 |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP and FRT-flanked neomycin selection cassette were inserted upstream of exon 16 and a second loxP site was inserted downstream of exon 19. Flp-mediated recombination removed the neomycin selection cassette. Cre-mediated recombination deleted exons 16-19, fusing exons 15 and 20 to create an out-of-frame transcript. |