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Protein Coding Gene : Mark4 MAP/microtubule affinity regulating kinase 4

Primary Identifier  MGI:1920955 Organism  mouse, laboratory
Chromosome  7 NCBI Gene Number  232944
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables cytoskeletal anchor activity. Involved in positive regulation of NLRP3 inflammasome complex assembly. Is active in microtubule organizing center. Orthologous to human MARK4 (microtubule affinity regulating kinase 4).
PHENOTYPE: Mice homozygous for a gene trap allele exhibit insulin hypersensitivity and resistance to diet-induced obersity. [provided by MGI curators]
  • synonyms:
  • Mark4,
  • MGI:2142337,
  • C79806,
  • Markl1,
  • MAP/microtubule affinity regulating kinase 4,
  • RIKEN cDNA 2410090P21 gene,
  • 2410090P21Rik,
  • expressed sequence C79806

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For