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Publication : Characterization of the mouse gene encoding the neuronal intermediate filament protein alpha-internexin.

First Author  Chien CL Year  1994
Journal  Gene Volume  149
Issue  2 Pages  289-92
PubMed ID  7959004 Mgi Jnum  J:21623
Mgi Id  MGI:69558 Doi  10.1016/0378-1119(94)90163-5
Citation  Chien CL, et al. (1994) Characterization of the mouse gene encoding the neuronal intermediate filament protein alpha-internexin. Gene 149(2):289-92
abstractText  We have determined the complete nucleotide (nt) sequence of the coding region of the mouse gene encoding the neuronal intermediate filament protein, alpha-internexin (alpha INX). The mouse alpha INX gene (m alpha INX) contains three exons and two introns, and may be classified as a member of the type-IV intermediate filament multigene family. The nt sequence of the transcribed region of m alpha INX shows high homology to that of the rat gene. Comparison of the deduced amino-acid sequences between the mouse and rat gene products reveals that the head and rod domains are highly conserved. However, the tail domains show significant differences which may make it possible to raise specific antibodies that can distinguish the alpha INX of mouse from that of rat.
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