Primary Identifier | MGI:5576170 | Allele Type | Transgenic |
Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(Myh6-TNNT2*R141W)#Lian |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false |
description | Three lines were established: 1, 13, and 16. |
molecularNote | This transgene consists of the Myh6 promoter driving expression of a full-length human TNNT2 cDNA containing a T to C substitution at position 520 that results in the R141W mutation. Northern blot and immunohistochemistry confirmed expression. Three lines were established: 1, 13, and 16, however the pound symbol (#) is used because the lines are pooled. |