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Publication : The human interleukin-6 receptor alpha chain gene is localized on chromosome 1 band q21.

First Author  Kluck PM Year  1993
Journal  Hum Genet Volume  90
Issue  5 Pages  542-4
PubMed ID  8428753 Mgi Jnum  J:4244
Mgi Id  MGI:52740 Doi  10.1007/BF00217455
Citation  Kluck PM, et al. (1993) The human interleukin-6 receptor alpha chain gene is localized on chromosome 1 band q21. Hum Genet 90(5):542-4
abstractText  The human interleukin-6 receptor alpha chain (IL6R alpha) gene was regionally mapped to chromosome 1 band q21 by fluorescence in situ hybridization. As hybridization probes, partially overlapping lambda clones encompassing 28 kb of the genomic region of the gene were used. These clones were isolated using a polymerase chain reaction (PCR)-generated fragment of the 3' non-coding region of the gene. This localization confirms and extends the provisional assignment of the IL6R alpha gene to chromosome 1, for which a panel of somatic cell hybrids was used.
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