Primary Identifier | MGI:98107 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 20044 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) A structural constituent of ribosome. Predicted to be involved in several processes, including erythrocyte differentiation; negative regulation of transcription by RNA polymerase II; and ribosomal small subunit assembly. Located in mitochondrion. Part of cytosolic small ribosomal subunit. Is active in synapse. Is expressed in early conceptus and metanephros. Human ortholog(s) of this gene implicated in chromosome 5q deletion syndrome. Orthologous to human RPS14 (ribosomal protein S14). PHENOTYPE: Conditional heterozygous knockout in hematopoietic cells leads to reduced protein synthesis, resulting in progressive anemia. [provided by MGI curators] |