Primary Identifier | IPR016666 | Type | Family |
Short Name | TGFBI/POSTN |
description | This entry includes TGF beta-induced protein (TGFBI, also known as betaig-H3 and keratoepithelin) and Periostin. They are are paralogues that contain a single emilin (EMI) and four fasciclin-1 (FAS1) modules and are secreted from cells []. Transforming growth factor-beta-induced protein is an extracellular matrix protein that plays a role in a wide range of physiological and pathological conditions including diabetes, corneal dystrophy and tumorigenesis [].Periostin (also known as osteoblast-specific factor 2), is a secreted cell adhesion protein, which has been linked to cancer, and degenerative/allergic diseases [, ]. |