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Protein Domain : Leukocyte surface antigen CD47

Primary Identifier  IPR006704 Type  Family
Short Name  CD47
description  Leukocyte surface antigen CD47 (also known as integrin-associated protein, IAP) is a widely expressed membrane protein with multiple functions in immunological and neuronal processes. For example, CD47-induces caspase-independent cell death which may be mediated by cytoskeleton reorganisation []. In red blood cells, CD47 acts like a marker of self by ligating the macrophage inhibitory receptor signal regulatory protein alpha []. The protein can also act as a thrombospondin receptor [].This entry also includes a group of CD-47-like proteins found in poxviruses (Poxviridae) such as protein A38 [].

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12 Protein Domain Regions