Primary Identifier | MGI:4442490 | Allele Type | Targeted |
Gene | Fbln5 | Transmission | Germline |
Strain of Origin | 129S6/SvEvTac | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Aspartic acid codon 56 (GAC) the integrin-binding RGD sequence in exon 4 was changed to glutamic acid (GAG) (p.D56E). The protein product is predicted to be deficient in integrin-binding. A loxP flanked neomycin resistance gene cassette used for selection was removed by Cre-mediated recombination. |