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Protein Coding Gene : Otud3 OTU domain containing 3
Primary Identifier  MGI:1920412 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  73162
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in cellular response to nutrient levels and protein stabilization. Predicted to act upstream of or within negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in axial skeleton; olfactory epithelium; pancreas; and vomeronasal organ. Orthologous to human OTUD3 (OTU deubiquitinase 3).
PHENOTYPE: Homozygous knockout results in decreased susceptibility to RNA virus infection. [provided by MGI curators]
  • synonyms:
  • 3110030K17Rik,
  • Otud3,
  • RIKEN cDNA 3110030K17 gene,
  • OTU domain containing 3
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Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

9 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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