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Protein Coding Gene : Casp7 caspase 7
Primary Identifier  MGI:109383 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  12369
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables aspartic-type endopeptidase activity and cysteine-type endopeptidase activity involved in apoptotic process. Involved in lymphocyte apoptotic process and protein maturation. Acts upstream of or within several processes, including execution phase of apoptosis; fibroblast apoptotic process; and neuron apoptotic process. Is active in extracellular space. Is expressed in brain; foregut; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in Alzheimer's disease; breast cancer; colon cancer; and lung non-small cell carcinoma. Orthologous to human CASP7 (caspase 7).
PHENOTYPE: Mice homozygous for a targeted mutation have normal appearance, organ morphology and lymphoid development. [provided by MGI curators]
  • synonyms:
  • AI314680,
  • caspase-7,
  • MGI:2147501,
  • expressed sequence AI314680,
  • Casp7,
  • ICE-IAP3,
  • CMH-1,
  • Mch3,
  • caspase 7,
  • MGD-MRK-38428
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Features --> Cross References

Genome

Sequence Feature Displayer

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

12 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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