| First Author | Grigoriou M | Year | 1995 |
| Journal | Genomics | Volume | 26 |
| Issue | 3 | Pages | 550-5 |
| PubMed ID | 7607679 | Mgi Jnum | J:25241 |
| Mgi Id | MGI:72968 | Doi | 10.1016/0888-7543(95)80174-k |
| Citation | Grigoriou M, et al. (1995) Isolation of the human MOX2 homeobox gene and localization to chromosome 7p22.1-p21.3. Genomics 26(3):550-5 |
| abstractText | We have isolated and characterized cDNA clones encoding a novel human homeobox gene, MOX2, the homologue of the murine mox-2 gene. The MOX2 protein contains all of the characteristic features of Mox-2 proteins of other vertebrate species, namely the homeobox, the polyhistidine stretch, and a number of potential serine/threonine phosphorylation sites. The homeodomain of MOX2 protein is identical to all other vertebrate species reported so far (rodents and amphibians). Outside the homeodomain, Mox-2 proteins share a high degree of identity, except for a few amino acid differences encountered between the human and the rodent polypeptides. A polyhistidine stretch of 12 amino acids in the N terminal region of the protein is also conserved among humans, rodents, and (only partly) amphibians. The chromosomal position of MOX2 was assigned to 7p22.1-p21.3. |
