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Protein Domain : 2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1

Primary Identifier  IPR028607 Type  Family
Short Name  DNPH1
description  DNPH1 (also known as Rcl) is an enzyme involved in nucleotide metabolism. It catalyses the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base []. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases. This enzyme is over-expressed in several cancers [], which may be a potential molecular target for cancer treatment [].

0 Child Features

1 Parent Features

1 Protein Domain Regions