Primary Identifier | IPR028607 | Type | Family |
Short Name | DNPH1 |
description | DNPH1 (also known as Rcl) is an enzyme involved in nucleotide metabolism. It catalyses the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base []. Deoxyribonucleoside 5'-monophosphates containing purine bases are preferred to those containing pyrimidine bases. This enzyme is over-expressed in several cancers [], which may be a potential molecular target for cancer treatment []. |