First Author | Paigen K | Year | 1979 |
Journal | Science | Volume | 203 |
Issue | 4380 | Pages | 554-6 |
PubMed ID | 760204 | Mgi Jnum | J:6080 |
Mgi Id | MGI:54557 | Doi | 10.1126/science.760204 |
Citation | Paigen K, et al. (1979) A regulatory locus for mouse beta-glucuronidase induction, Gur, controls messenger RNA activity. Science 203(4380):554-6 |
abstractText | A regulatory locus in a higher organism has been shown to control a specific messenger RNA activity. The Gur locus in mice regulates the production of kidney beta-glucuronidase messenger RNA activity after induction of the beta-glucuronidase structural gene, Gus, by testosterone. beta-Glucuronidase messenger RNA was assayed by its ability to direct the synthesis of catalytically active murine beta-glucuronidase in Xenopus oocytes. |