|  Help  |  About  |  Contact Us

Protein Domain : Dual oxidase 2

Primary Identifier  IPR034818 Type  Family
Short Name  DUOX2
description  This entry represents dual oxidase 2 (DUOX2). DUOX1 and DUOX2 are isoenzymes that belong to the family of NADPH oxidases (Nox) []. They function as calcium-dependent NADPH oxidases producing hydrogen peroxide (H2O2) which is required for thyroid hormone biosynthesis []and the activity of lactoperoxidase (LPO) []. Duox2 is activated by activation of protein kinase C (PKC) and can be suppressed by thyroglobulin (Tg) [, ].

0 Child Features

1 Parent Features

4 Protein Domain Regions