First Author | Frank SL | Year | 1989 |
Journal | Genomics | Volume | 5 |
Issue | 3 | Pages | 646-8 |
PubMed ID | 2575592 | Mgi Jnum | J:10261 |
Mgi Id | MGI:58714 | Doi | 10.1016/0888-7543(89)90037-2 |
Citation | Frank SL, et al. (1989) Linkage of the mouse LDL receptor gene on chromosome 9. Genomics 5(3):646-8 |
abstractText | We identified restriction fragment length variants of the mouse low-density lipoprotein receptor gene and used these to map the gene, designated Ldlr, to the proximal region of chromosome 9. An interspecific backcross between strains MEV and CAST/Ei yielded the following gene order and distances in centimorgans: Ldlr-18.8 +/- 5.6-Apoa-4-7.3 +/- 3.5-Mpi-1-10.2 +/- 3.9-Emv-3 or dilute. Analysis of recombinant inbred strains also indicated that Ldlr is tightly linked to a previously unmapped retroviral marker, Xmmv-67. |