Primary Identifier | MGI:5140888 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Pdgfrb |
Transmission | Germline | Strain of Origin | 129S4/SvJaeSor |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 2 and 3 were replaced with a splice acceptor, floxed neo/stop cassette, and the mouse cDNA with nucleotide substitution(s) that results in the amino acid substitution of alanine for valine at position 536 (V536A). This mutation is an activating mutation. |