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Publication : Potassium channels from NG108-15 neuroblastoma-glioma hybrid cells. Primary structure and functional expression from cDNAs.

First Author  Yokoyama S Year  1989
Journal  FEBS Lett Volume  259
Issue  1 Pages  37-42
PubMed ID  2599109 Mgi Jnum  J:40342
Mgi Id  MGI:87683 Doi  10.1016/0014-5793(89)81488-7
Citation  Yokoyama S, et al. (1989) Potassium channels from NG108-15 neuroblastoma-glioma hybrid cells. Primary structure and functional expression from cDNAs. FEBS Lett 259(1):37-42
abstractText  The complete amino acid sequences of two potassium channel proteins from NG108-15 neuroblastoma-glioma hybrid cells have been deduced by cloning and sequencing the cDNAs. One of these proteins (NGK2) is structurally more closely related to the Drosophila Shaw gene product than to the Shaker and Shab gene products, whereas the other (NGK1) is identical with a rat brain potassium channel protein (BK2) which is more closely related to the Drosophila Shaker gene product. mRNAs derived from both the cloned cDNAs, when injected into Xenopus oocytes, direct the formation of functional potassium channels with properties of delayed rectifiers.
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