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Protein Domain : Kelch-like protein 42, BTB and C-terminal Kelch domain

Primary Identifier  IPR044727 Type  Domain
Short Name  KLHL42_BACK
description  This entry represents the BTB and C-terminal Kelch domain found in KLHL42, which is a substrate-specific adaptor of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL42) E3 ubiquitin ligase complex mediates the ubiquitination and subsequent degradation of KATNA1. KLHL42 is involved in microtubule dynamics throughout mitosis [].

0 Child Features

0 Parent Features

2 Protein Domain Regions