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ncRNA Gene : Mir21a microRNA 21a

Primary Identifier  MGI:2676885 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  387140
Mgi Type  miRNA gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables mRNA 3'-UTR binding activity. Involved in miRNA-mediated post-transcriptional gene silencing. Acts upstream of or within several processes, including cellular response to cytokine stimulus; cellular response to dexamethasone stimulus; and regulation of gene expression. Part of RISC complex. Is expressed in lung.
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal cardiac morphology and response to stress, with the exception of a mildly exaggerated increase in heart weight in Ang II-treated mice. [provided by MGI curators]
  • synonyms:
  • Mirn21,
  • microRNA 21,
  • Mir21a,
  • Mir21,
  • mmu-mir-21a,
  • microRNA 21a,
  • mmu-mir-21

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

Trail: NcRNAGene

0 Strain

0 Transcripts

4 Transgenic Expressors

Trail: NcRNAGene

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Targeted By

0 Targets

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For