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Allele : Tcra<tm1Mass> T cell receptor alpha chain; targeted mutation 1, Marc Schmidt-Supprian

Primary Identifier  MGI:5532653 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Tcra
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  The targeting construct inserted between the Jalpha and C alpha exons four polyadenylation sequences, a 1.8 kb of upstream regulatory sequence, the Valpha14 promoter, a leader sequence, a floxed stop cassette, the sequence for the Valpha14 and Jalpha18 invariant (Valpha14i) arrangement expressed in most NKT cells and a 0.2 kb intronic sequence. This insertion abolishes TCRalpha expression.
  • mutations:
  • Insertion
  • synonyms:
  • Valpha14i<StopF>,
  • Valpha14i<StopF>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

6 Publication categories

Trail: Allele