| Primary Identifier | MGI:107704 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 11307 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable several functions, including ABC-type sterol transporter activity; adenyl ribonucleotide binding activity; and protein dimerization activity. Involved in several processes, including cholesterol transport; plasma lipoprotein particle remodeling; and positive regulation of cholesterol biosynthetic process. Acts upstream of or within cholesterol transport. Located in external side of plasma membrane and recycling endosome. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human ABCG1 (ATP binding cassette subfamily G member 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal lipid homeostasis, increased numbers of multiple immune cell types, and abnormal response to a high fat diet. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
