Primary Identifier | MGI:2429498 | Organism | mouse, laboratory |
Chromosome | 10 | NCBI Gene Number | 210198 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables G protein-coupled receptor activity. Involved in regulation of testosterone biosynthetic process and response to amino acid. Is active in plasma membrane. Is expressed in several structures, including femur; liver; male reproductive gland or organ; musculature; and spleen. Orthologous to human GPRC6A (G protein-coupled receptor class C group 6 member A). PHENOTYPE: Mice homozygous for a knock-out allele show a metabolic syndrome characterized by impaired bone mineralization, increased fat mass, abnormal renal handling of calcium and phosphorus, fatty liver, glucose intolerance, testicular feminization and abnormal steroidogenesis. [provided by MGI curators] |