| Primary Identifier | MGI:2388479 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 226849 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable kinase binding activity; phosphoprotein phosphatase activity; and protein phosphatase activator activity. Predicted to be involved in negative regulation of protein localization to plasma membrane and positive regulation of protein dephosphorylation. Located in M band and Z disc. Is expressed in several structures, including brain; gonad; hemolymphoid system gland; liver; and neural retina. Orthologous to human PPP2R5A (protein phosphatase 2 regulatory subunit B'alpha). PHENOTYPE: Mice homozygous for a gene trap allele are hypomorphic, with the severely reduced expression causing development of spontaneous skin lesions combined with hair loss and enlarged liver, spleen and lymph nodes. They are also more susceptible to chemically induced skin tumors. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
