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Protein Coding Gene : Plin5 perilipin 5

Primary Identifier  MGI:1914218 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  66968
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables identical protein binding activity and lipase binding activity. Involved in several processes, including negative regulation of peroxisome proliferator activated receptor signaling pathway; positive regulation of sequestering of triglyceride; and regulation of lipid metabolic process. Located in cytosol and lipid droplet. Is expressed in brown fat. Orthologous to human PLIN5 (perilipin 5).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit excessive fatty acid oxidation, abnormal lipid levels in organs depending on fed or fasted state, increased oxygen consumption and activity in the dark phase, and decreased cardiac muscle contractility in aged mice. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 2310076L09 gene,
  • expressed sequence AW109675,
  • expressed sequence AI415325,
  • MGI:2147046,
  • MLDP,
  • Lsdp5,
  • AI415325,
  • MGI:2146846,
  • 2310076L09Rik,
  • AW109675,
  • perilipin 5,
  • Plin5

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For